HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: CDC53 (Q12018)
Cell division control protein 53 (Cullin-A) (E3 ubiquitin ligase complex SCF subunit CDC53)
Gene: CDC53

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.594

Property	Details
Experiments	11805837, 37295430
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 815
+	Hs
		438150 HS90B_HUMAN (5-705): 0: 1022: 61.15		CUL1_HUMAN (7-815): 0: 741: 29.92
+	Hs
		431829 HS90A_HUMAN (4-705): 0: 1013: 60.67		CUL1_HUMAN (7-815): 0: 741: 29.92
+	Sc
		367047 HSP82_YEAST (1-705): 0: 968: 95.63		CDC53_YEAST (1-815): 0: 773: 100.00
+	Hs
		438153 HS90B_HUMAN (5-705): 0: 1022: 61.15		CUL4A_HUMAN (6-815): 0: 701: 21.29
+	Hs
		438152 HS90B_HUMAN (5-705): 0: 1022: 61.15		CUL3_HUMAN (10-815): 0: 696: 21.12
+	Hs
		438154 HS90B_HUMAN (5-705): 0: 1022: 61.15		CUL4B_HUMAN (5-815): 0: 695: 21.14
+	Hs
		431832 HS90A_HUMAN (4-705): 0: 1013: 60.67		CUL4A_HUMAN (6-815): 0: 701: 21.29
+	Hs
		431831 HS90A_HUMAN (4-705): 0: 1013: 60.67		CUL3_HUMAN (10-815): 0: 696: 21.12
+	Hs
		431833 HS90A_HUMAN (4-705): 0: 1013: 60.67		CUL4B_HUMAN (5-815): 0: 695: 21.14
+	Hs
		438151 HS90B_HUMAN (5-705): 0: 1022: 61.15		CUL2_HUMAN (3-815): 0: 671: 26.08
+	Hs
		431830 HS90A_HUMAN (4-705): 0: 1013: 60.67		CUL2_HUMAN (3-815): 0: 671: 26.08
+	Hs
		538224 ENPL_HUMAN (3-680): 0: 893: 47.10		CUL1_HUMAN (7-815): 0: 741: 29.92
+	Hs
		438412 HS90B_HUMAN (5-705): 0: 1022: 61.15		CUL5_HUMAN (8-815): 0: 590: 20.84
+	Hs
		432131 HS90A_HUMAN (4-705): 0: 1013: 60.67		CUL5_HUMAN (8-815): 0: 590: 20.84
+	Hs
		538227 ENPL_HUMAN (3-680): 0: 893: 47.10		CUL4A_HUMAN (6-815): 0: 701: 21.29
+	Hs
		538226 ENPL_HUMAN (3-680): 0: 893: 47.10		CUL3_HUMAN (10-815): 0: 696: 21.12
+	Hs
		538228 ENPL_HUMAN (3-680): 0: 893: 47.10		CUL4B_HUMAN (5-815): 0: 695: 21.14
+	Hs
		538225 ENPL_HUMAN (3-680): 0: 893: 47.10		CUL2_HUMAN (3-815): 0: 671: 26.08
+	Hs
		538342 ENPL_HUMAN (3-680): 0: 893: 47.10		CUL5_HUMAN (8-815): 0: 590: 20.84