Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82
Interactor 2: AHA1 (Q12449)
Hsp90 co-chaperone AHA1 (Activator of Hsp90 ATPase protein 1)
Gene: AHA1
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.979 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15633294, 31399574, 37295430, 37453059, 20159554, 16554755, 16429126, 18719252, 37968396, 24614167, 19536198, 15766533 |
| Identification Methods | two hybrid, affinity chromatography technology, fluorescent resonance energy transfer, x-ray crystallography, pull down, tandem affinity purification |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Aha1_N~HSP90, AHSA1~HSP90 |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006457 - protein folding |
| Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
