HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: YPT6 (Q99260)
GTP-binding protein YPT6
Gene: YPT6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	16554755, 19536198, 15766533
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 215
+	Mm
		513667 HS90B_MOUSE (5-705): 0: 1025: 61.57		RAB1A_MOUSE (1-215): 1.85e-84: 250: 33.33
+	Mm
		432417 HS90A_MOUSE (4-705): 0: 1012: 60.59		RAB1A_MOUSE (1-215): 1.85e-84: 250: 33.33
+	Sc
		350841 HSC82_YEAST (1-705): 0: 977: 100.00		YPT1_YEAST (11-215): 1.69e-84: 250: 34.15
+	Sc
		350829 HSP82_YEAST (1-705): 0: 968: 95.63		YPT1_YEAST (11-215): 1.69e-84: 250: 34.15
+	Sc
		367160 HSP82_YEAST (1-705): 0: 968: 95.63		YPT6_YEAST (1-215): 4.28e-83: 247: 100.00
+	Hs
		538180 ENPL_HUMAN (3-680): 0: 893: 47.10		RAB8A_HUMAN (11-215): 2.51e-89: 263: 39.02
+	Sc
		543535 HSC82_YEAST (1-705): 0: 977: 100.00		VPS21_YEAST (7-215): 9.74e-42: 142: 38.07
+	Dm
		185627 Q9VAY2_DROME (3-676): 0: 833: 47.09		RAB6_DROME (5-183): 3.4e-82: 244: 69.27
+	Dm
		185551 Q9VAY2_DROME (3-676): 0: 833: 47.09		RAB2_DROME (1-214): 3.2e-80: 240: 33.79
+	Mm
		435916 ENPL_MOUSE (3-705): 0: 897: 46.03		RAB5C_MOUSE (4-196): 1.07e-45: 152: 38.00
+	Dm
		1358711 Q9VAY2_DROME (3-676): 0: 833: 47.09		RAB5_DROME (10-175): 9.57e-42: 142: 40.96