HitPredict

Interactor 1: INSR (P15127)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Interactor 2: CP270 (P19225)
Cytochrome P450 2C70 (EC 1.14.14.-) (CYPIIC70) (Cytochrome P-450Md) (Cytochrome P450 P49)
Gene: Cyp2c70

Species: Rattus norvegicus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	30300385
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1383 Rn			1 489
+	Rn
		544842 INSR_RAT (1-1383): 0: 1575: 100.00		Q4QQW7_RAT (1-488): 0: 552: 59.51
+	Rn
		398435 INSR_RAT (1-1383): 0: 1575: 100.00		CP2C7_RAT (1-488): 0: 550: 59.51
+	Rn
		398450 INSR_RAT (1-1383): 0: 1575: 100.00		CP2E1_RAT (1-488): 0: 518: 51.33
+	Rn
		544777 INSR_RAT (1-1383): 0: 1575: 100.00		CP2CN_RAT (1-488): 2.43e-177: 508: 52.54
+	Rn
		398434 INSR_RAT (1-1383): 0: 1575: 100.00		CP2C6_RAT (13-489): 3.63e-174: 500: 60.25
+	Rn
		544884 INSR_RAT (1-1383): 0: 1575: 100.00		Q64648_RAT (18-489): 6.18e-174: 499: 56.45
+	Rn
		514662 INSR_RAT (1-1383): 0: 1575: 100.00		CP2A1_RAT (3-489): 1.85e-170: 491: 44.26
+	Rn
		525792 INSR_RAT (1-1383): 0: 1575: 100.00		CP2B3_RAT (41-487): 8.03e-159: 461: 43.30
+	Rn
		496151 INSR_RAT (1-1383): 0: 1575: 100.00		CP2DQ_RAT (41-487): 3.87e-151: 441: 36.73
+	Rn
		496150 INSR_RAT (1-1383): 0: 1575: 100.00		CP2D1_RAT (1-487): 3.5e-147: 432: 35.57
+	Rn
		388919 INSR_RAT (1-1383): 0: 1575: 100.00		CP1A2_RAT (5-470): 9.89e-60: 206: 30.25
+	Hs
		396515 IGF1R_HUMAN (13-1381): 0: 1302: 55.77		CP17A_HUMAN (57-458): 1.14e-54: 192: 31.72
+	At
		85270 PAM74_ARATH (504-1322): 8.09e-173: 540: 12.27		C71BJ_ARATH (1-489): 1.74e-155: 453: 23.15
+	At
		85142 PAM74_ARATH (504-1322): 8.09e-173: 540: 12.27		C83A1_ARATH (1-488): 6.4e-155: 451: 25.75
+	Hs
		665319 EPHA2_HUMAN (662-1321): 2.76e-167: 528: 22.70		CP2S1_HUMAN (50-488): 9.68e-158: 458: 42.31
+	Hs
		398430 EPHA4_HUMAN (662-1328): 0: 570: 24.19		CP1A2_HUMAN (5-471): 1.41e-57: 200: 27.55
+	Hs
		383523 ERBB2_HUMAN (32-342): 4.75e-18: 92.8: 19.83		CP17A_HUMAN (57-458): 1.14e-54: 192: 31.72