HitPredict

Interactor 1: INSR (P15127)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Interactor 2: IRS1 (P35570)
Insulin receptor substrate 1 (IRS-1) (pp185)
Gene: IRS1

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 15924411
Identification Methods pull down
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~PK_Tyr_Ser-Thr
Common GO terms GO:0005159 - insulin-like growth factor receptor binding
GO:0005886 - plasma membrane
GO:0005899 - insulin receptor complex
GO:0005901 - caveola
GO:0008286 - insulin receptor signaling pathway
and 11 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1383
Rn

1 1235
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024