Interactor 1: AMPN (P15144)
Aminopeptidase N (AP-N) (hAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (Myeloid plasma membrane glycoprotein CD13) (gp150) (CD antigen CD13)
Gene: ANPEP

Interactor 2: LCAP (Q9UIQ6)
Leucyl-cystinyl aminopeptidase (Cystinyl aminopeptidase) (EC 3.4.11.3) (Insulin-regulated membrane aminopeptidase) (Insulin-responsive aminopeptidase) (IRAP) (Oxytocinase) (OTase) (Placental leucine aminopeptidase) (P-LAP) [Cleaved into: Leucyl-cystinyl aminopeptidase, pregnancy serum form]
Gene: LNPEP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 34709727
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ERAP1_C~ERAP1_C, ERAP1_C~Peptidase_M1, ERAP1_C~Peptidase_M1_N, Peptidase_M1~Peptidase_M1, Peptidase_M1~Peptidase_M1_N, Peptidase_M1_N~Peptidase_M1_N
Common GO terms GO:0004177 - aminopeptidase activity
GO:0005615 - extracellular space
GO:0005737 - cytoplasm
GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane
and 6 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 967
Hs

1 1025
+ Hs
+ Mm
+ Dm
+ Dm
+ Dm
+ Sc

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Last updated: 15 Jul 2024