Interactor 1: PVR (P15151)
Poliovirus receptor (Nectin-like protein 5) (NECL-5) (CD antigen CD155)
Gene: PVR

Interactor 2: NECT1 (Q15223)
Nectin-1 (Herpes virus entry mediator C) (Herpesvirus entry mediator C) (HveC) (Herpesvirus Ig-like receptor) (HIgR) (Nectin cell adhesion molecule 1) (Poliovirus receptor-related protein 1) (CD antigen CD111)
Gene: NECTIN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 22902367
Identification Methods surface plasmon resonance
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains C2-set_2~C2-set_2, C2-set_2~Ig_3, C2-set_2~V-set, Ig_3~V-set, V-set~V-set
Common GO terms GO:0001618 - virus receptor activity
GO:0005886 - plasma membrane
GO:0005912 - adherens junction
GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007157 - heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
and 3 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 417
Hs

1 517
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Mm
+ Dm
+ Dm
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024