HitPredict

Interactor 1: PVR (P15151)
Poliovirus receptor (Nectin-like protein 5) (NECL-5) (CD antigen CD155)
Gene: PVR

Interactor 2: BTNL2 (Q9UIR0)
Butyrophilin-like protein 2 (BTL-II)
Gene: BTNL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	C2-set_2~V-set, V-set~V-set
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 417 Hs			1 482
+	Hs
		1343562 NECT3_HUMAN (26-389): 5.45e-69: 229: 24.20		BTNL2_HUMAN (1-482): 2.36e-96: 300: 100.00
+	Dr
		69465 B0CLW6_DANRE (11-330): 4.83e-68: 220: 33.44		Q2YDQ1_DANRE (244-476): 2.83e-55: 188: 26.70
+	Dm
		1372240 Q9VQ08_DROME (28-372): 2.1e-38: 149: 15.04		Q9VQ08_DROME (29-463): 3.81e-32: 132: 12.80
+	Hs
		1378225 ROBO1_HUMAN (19-407): 1.02e-47: 177: 15.50		ROBO1_HUMAN (20-264): 1.37e-21: 100: 13.83
+	Hs
		1336275 ROBO1_HUMAN (19-407): 1.02e-47: 177: 15.50		ROBO2_HUMAN (20-480): 3.08e-21: 99.4: 11.49
+	Hs
		1336269 ROBO2_HUMAN (28-347): 3.03e-46: 172: 14.59		ROBO2_HUMAN (20-480): 3.08e-21: 99.4: 11.49
+	Dm
		1372236 Q9VPZ7_DROME (12-347): 6.5e-19: 91.6: 11.72		Q9VPZ7_DROME (228-480): 7.92e-35: 140: 12.12
+	Dm
		1325660 Q9GPP6_DROME (12-347): 7.52e-19: 91.2: 11.72		Q9GPP6_DROME (228-480): 8.77e-35: 140: 12.12
+	Mm
		1149039 CNTN4_MOUSE (145-417): 1.02e-29: 123: 13.33		CNTN4_MOUSE (20-224): 5.04e-14: 76.7: 15.24
+	Rn
		222935 ROBO1_RAT (19-403): 2.42e-28: 120: 12.74		DCC_RAT (353-480): 4.26e-11: 67.8: 13.70
+	Dm
		1281064 Q9VQW7_DROME (28-338): 1.49e-12: 71.7: 15.27		TUTL_DROME (255-478): 3.07e-26: 115: 16.67
+	Mm
		530206 CNTN2_MOUSE (24-327): 1.89e-27: 117: 17.30		NCAM1_MOUSE (354-480): 3.93e-11: 67.8: 12.59
+	Dm
		1372761 Q9VQW1_DROME (45-335): 6.08e-17: 85.2: 20.26		Q9VQW7_DROME (45-460): 2.15e-15: 81.3: 18.16
+	Dm
		90 A0A023GPK8_DROME (45-335): 1.6e-16: 84.1: 20.26		Q9VQW7_DROME (45-460): 2.15e-15: 81.3: 18.16
+	Dm
		1372779 Q9VQW7_DROME (28-338): 1.49e-12: 71.7: 15.27		Q9VQW7_DROME (45-460): 2.15e-15: 81.3: 18.16
+	Ce
		103933 SAX3_CAEEL (18-154): 2.03e-10: 65: 17.52		SAX3_CAEEL (1-177): 2.04e-10: 65.5: 13.81
+	Hs
		1264771 TITIN_HUMAN (178-333): 3.86e-09: 61.2: 11.25		TITIN_HUMAN (368-479): 1.48e-09: 62.8: 12.39
+	Dm
		219801 O44924_DROME (16-165): 8.86e-09: 59.6: 14.84		O44924_DROME (16-160): 6.41e-09: 60.9: 12.41