HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: CXA1 (P17302)
Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein)
Gene: GJA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0007165 - signal transduction
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 382
+	Hs
		566998 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		CXA1_HUMAN (1-382): 0: 545: 100.00
+	Hs
		564408 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		CXA1_HUMAN (1-382): 0: 545: 100.00
+	Hs
		566989 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		CXA1_HUMAN (1-382): 0: 545: 100.00
+	Hs
		567008 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		CXA1_HUMAN (1-382): 0: 545: 100.00
+	Hs
		566990 CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75		CXA1_HUMAN (1-382): 0: 545: 100.00
+	Hs
		566992 RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26		CXA1_HUMAN (1-382): 0: 545: 100.00
+	Hs
		436147 RHOC_HUMAN (5-192): 1.83e-73: 221: 54.79		CXA1_HUMAN (1-382): 0: 545: 100.00
+	Hs
		734406 RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26		CXG1_HUMAN (4-373): 1.81e-130: 381: 32.49