HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: CTR1 (P30825)
High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homolog) (Ecotropic retrovirus receptor homolog) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter)
Gene: SLC7A1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 629
+	Hs
		676533 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00
+	Hs
		676527 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00
+	Hs
		676536 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00
+	Hs
		854874 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61
+	Hs
		564457 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61
+	Hs
		545280 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61
+	Hs
		854865 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61
+	Hs
		854876 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61
+	Hs
		925480 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		YLAT2_HUMAN (8-494): 6.88e-98: 310: 18.74
+	Hs
		925205 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		LAT1_HUMAN (22-440): 6.07e-94: 300: 20.24
+	Hs
		564484 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		LAT1_HUMAN (22-440): 6.07e-94: 300: 20.24
+	Hs
		545328 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		LAT1_HUMAN (22-440): 6.07e-94: 300: 20.24
+	Hs
		951194 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		YLAT2_HUMAN (8-494): 6.88e-98: 310: 18.74
+	Hs
		892323 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		LAT1_HUMAN (22-440): 6.07e-94: 300: 20.24
+	Hs
		950931 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		LAT1_HUMAN (22-440): 6.07e-94: 300: 20.24
+	Hs
		951440 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		S12A6_HUMAN (4-490): 5.77e-88: 298: 11.86
+	Hs
		925739 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		XCT_HUMAN (19-466): 5.04e-82: 268: 19.15
+	Hs
		564743 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		XCT_HUMAN (19-466): 5.04e-82: 268: 19.15
+	Hs
		545702 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		XCT_HUMAN (19-466): 5.04e-82: 268: 19.15
+	Hs
		892685 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		XCT_HUMAN (19-466): 5.04e-82: 268: 19.15