HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: VAMP7 (P51809)
Vesicle-associated membrane protein 7 (VAMP-7) (Synaptobrevin-like protein 1) (Tetanus-insensitive VAMP) (Ti-VAMP)
Gene: VAMP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane GO:0030027 - lamellipodium GO:0030670 - phagocytic vesicle membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 220
+	Hs
		850556 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		VAMP7_HUMAN (1-220): 3.87e-90: 266: 100.00
+	Hs
		564456 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		VAMP7_HUMAN (1-220): 3.87e-90: 266: 100.00
+	Hs
		850548 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		VAMP7_HUMAN (1-220): 3.87e-90: 266: 100.00
+	Hs
		850558 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		VAMP7_HUMAN (1-220): 3.87e-90: 266: 100.00
+	Hs
		850550 CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75		VAMP7_HUMAN (1-220): 3.87e-90: 266: 100.00
+	Hs
		263218 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		SC22B_HUMAN (23-206): 4.4e-59: 186: 22.16
+	Hs
		263159 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		SC22B_HUMAN (23-206): 4.4e-59: 186: 22.16
+	Hs
		180857 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		YKT6_HUMAN (23-179): 3.99e-55: 176: 23.42
+	Hs
		180807 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		YKT6_HUMAN (23-179): 3.99e-55: 176: 23.42
+	Hs
		263209 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		SC22B_HUMAN (23-206): 4.4e-59: 186: 22.16
+	Hs
		180804 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		YKT6_HUMAN (23-179): 3.99e-55: 176: 23.42
+	Hs
		263221 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		SC22B_HUMAN (23-206): 4.4e-59: 186: 22.16
+	Hs
		263210 CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75		SC22B_HUMAN (23-206): 4.4e-59: 186: 22.16
+	Hs
		180849 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		YKT6_HUMAN (23-179): 3.99e-55: 176: 23.42
+	Hs
		180859 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		YKT6_HUMAN (23-179): 3.99e-55: 176: 23.42
+	Hs
		180850 CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75		YKT6_HUMAN (23-179): 3.99e-55: 176: 23.42
+	Hs
		564666 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		VAMP8_HUMAN (114-193): 3.49e-13: 65.1: 41.25
+	Hs
		892567 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		VAMP8_HUMAN (114-193): 3.49e-13: 65.1: 41.25
+	Hs
		951283 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		VAMP8_HUMAN (114-193): 3.49e-13: 65.1: 41.25
+	Hs
		894374 CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75		VAMP8_HUMAN (114-193): 3.49e-13: 65.1: 41.25