HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: JAG1 (P78504)
Protein jagged-1 (Jagged1) (hJ1) (CD antigen CD339)
Gene: JAG1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 1218
+	Hs
		925184 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		JAG1_HUMAN (1-1218): 0: 690: 100.00
+	Hs
		892313 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		JAG1_HUMAN (1-1218): 0: 690: 100.00
+	Hs
		944117 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		JAG1_HUMAN (1-1218): 0: 690: 100.00
+	Hs
		925219 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		NOTC2_HUMAN (591-1041): 2.37e-45: 182: 24.42
+	Hs
		804195 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		NOTC1_HUMAN (22-654): 1.13e-44: 179: 20.73
+	Hs
		564491 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		NOTC2_HUMAN (591-1041): 2.37e-45: 182: 24.42
+	Hs
		545337 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		NOTC2_HUMAN (591-1041): 2.37e-45: 182: 24.42
+	Hs
		564446 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		NOTC1_HUMAN (22-654): 1.13e-44: 179: 20.73
+	Hs
		545253 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		NOTC1_HUMAN (22-654): 1.13e-44: 179: 20.73
+	Hs
		892331 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		NOTC2_HUMAN (591-1041): 2.37e-45: 182: 24.42
+	Hs
		804186 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		NOTC1_HUMAN (22-654): 1.13e-44: 179: 20.73
+	Hs
		950942 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		NOTC2_HUMAN (591-1041): 2.37e-45: 182: 24.42
+	Hs
		893926 CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75		NOTC2_HUMAN (591-1041): 2.37e-45: 182: 24.42
+	Hs
		804203 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		NOTC1_HUMAN (22-654): 1.13e-44: 179: 20.73
+	Hs
		804187 CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75		NOTC1_HUMAN (22-654): 1.13e-44: 179: 20.73
+	Hs
		900403 RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26		NOTC2_HUMAN (591-1041): 2.37e-45: 182: 24.42
+	Hs
		804189 RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26		NOTC1_HUMAN (22-654): 1.13e-44: 179: 20.73
+	Hs
		545674 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		TEN3_HUMAN (819-1027): 5.71e-25: 115: 12.15
+	Hs
		892650 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		TEN3_HUMAN (819-1027): 5.71e-25: 115: 12.15
+	Hs
		894539 CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75		TEN3_HUMAN (819-1027): 5.71e-25: 115: 12.15