HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: SNTB2 (Q13425)
Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin-3) (SNT3) (Syntrophin-like) (SNTL)
Gene: SNTB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras, PH~Ras
Common GO terms	GO:0005886 - plasma membrane GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 540
+	Hs
		925250 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		SNTB2_HUMAN (18-540): 1.13e-164: 480: 100.00
+	Hs
		564511 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		SNTB2_HUMAN (18-540): 1.13e-164: 480: 100.00
+	Hs
		892349 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		SNTB2_HUMAN (18-540): 1.13e-164: 480: 100.00
+	Hs
		950970 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		SNTB2_HUMAN (18-540): 1.13e-164: 480: 100.00
+	Hs
		564521 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		SNTB1_HUMAN (24-539): 2.43e-151: 445: 55.30
+	Hs
		158270 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		LIN7A_HUMAN (82-202): 4.94e-35: 133: 32.23
+	Hs
		1336631 V9HWD0_HUMAN (4-190): 1.9e-82: 244: 62.03		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		564695 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		925239 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		DLG1_HUMAN (2-419): 1.78e-27: 119: 15.51
+	Hs
		951362 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Mm
		925797 RAC1_MOUSE (1-192): 1.69e-84: 249: 92.19		DLG4_MOUSE (66-394): 4.96e-27: 117: 16.32
+	Hs
		564500 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		DLG1_HUMAN (2-419): 1.78e-27: 119: 15.51
+	Hs
		545346 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		DLG1_HUMAN (2-419): 1.78e-27: 119: 15.51
+	Mm
		1111996 Q3TLP8_MOUSE (1-192): 5.9e-80: 238: 83.41		DLG4_MOUSE (66-394): 4.96e-27: 117: 16.32
+	Hs
		892341 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		DLG1_HUMAN (2-419): 1.78e-27: 119: 15.51
+	Hs
		950954 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		DLG1_HUMAN (2-419): 1.78e-27: 119: 15.51
+	Hs
		564636 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		DLG3_HUMAN (117-399): 4.14e-22: 102: 15.97
+	Hs
		892525 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		DLG3_HUMAN (117-399): 4.14e-22: 102: 15.97
+	Hs
		951207 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		DLG3_HUMAN (117-399): 4.14e-22: 102: 15.97
+	Hs
		925536 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		MAGI1_HUMAN (69-261): 1.09e-15: 82.6: 17.96