HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: INF2 (Q27J81)
Inverted formin-2 (HBEBP2-binding protein C)
Gene: INF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Drf_FH3~Ras, Drf_GBD~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 1249
+	Hs
		925315 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		INF2_HUMAN (1-1249): 0: 873: 100.00
+	Hs
		925658 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		DIAP3_HUMAN (10-1092): 0: 666: 21.22
+	Hs
		564704 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		DIAP3_HUMAN (10-1092): 0: 666: 21.22
+	Hs
		545645 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		DIAP3_HUMAN (10-1092): 0: 666: 21.22
+	Hs
		243100 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		DIAP2_HUMAN (10-1018): 0: 642: 21.82
+	Hs
		243091 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		DIAP2_HUMAN (10-1018): 0: 642: 21.82
+	Hs
		243089 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		DIAP2_HUMAN (10-1018): 0: 642: 21.82
+	Hs
		314858 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		FMNL1_HUMAN (40-1009): 1.21e-173: 545: 19.70
+	Hs
		925531 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		FMNL2_HUMAN (10-1000): 6.58e-174: 545: 19.01
+	Hs
		314838 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		FMNL1_HUMAN (40-1009): 1.21e-173: 545: 19.70
+	Hs
		925768 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		FHOD1_HUMAN (8-1069): 2.59e-160: 511: 14.30
+	Dm
		776921 RAC1_DROME (1-192): 7.95e-82: 242: 89.06		FRL_DROME (71-1005): 8.87e-144: 468: 17.67
+	Hs
		925759 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		DAAM1_HUMAN (507-1016): 1.8e-110: 374: 23.54
+	Hs
		564754 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		DAAM1_HUMAN (507-1016): 1.8e-110: 374: 23.54
+	Hs
		545717 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		DAAM1_HUMAN (507-1016): 1.8e-110: 374: 23.54
+	Hs
		237586 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		DIAP1_HUMAN (10-532): 2.88e-73: 269: 21.30
+	Hs
		545484 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		FMNL3_HUMAN (43-382): 2.09e-59: 224: 20.68
+	Dm
		112307 RHO1_DROME (5-192): 3.82e-94: 273: 55.85		M9MRS9_DROME (4-403): 2.94e-42: 171: 14.52
+	Dm
		112306 RAC1_DROME (1-192): 7.95e-82: 242: 89.06		M9MRS9_DROME (4-403): 2.94e-42: 171: 14.52
+	Hs
		925673 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		FMN2_HUMAN (495-827): 8.34e-11: 68.9: 25.71