HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: MAVS (Q7Z434)
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Putative NF-kappa-B-activating protein 031N) (Virus-induced-signaling adapter) (VISA)
Gene: MAVS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005741 - mitochondrial outer membrane GO:0007165 - signal transduction GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 540
+	Hs
		892454 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00
+	Hs
		951111 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00
+	Hs
		894165 CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75		MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00
+	Hs
		900632 RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26		MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00
+	Mm
		925811 RAC1_MOUSE (1-192): 1.69e-84: 249: 92.19		MAVS_MOUSE (1-538): 5.1e-46: 170: 47.68
+	Hs
		297823 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		K0754_HUMAN (43-539): 5.17e-38: 151: 11.24
+	Hs
		297812 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		K0754_HUMAN (43-539): 5.17e-38: 151: 11.24
+	Hs
		297819 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		K0754_HUMAN (43-539): 5.17e-38: 151: 11.24
+	Hs
		297827 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		K0754_HUMAN (43-539): 5.17e-38: 151: 11.24
+	Hs
		297820 RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26		K0754_HUMAN (43-539): 5.17e-38: 151: 11.24
+	Hs
		925397 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36
+	Hs
		925724 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		ASAP1_HUMAN (95-423): 4.61e-23: 105: 13.43
+	Hs
		925387 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		MICA3_HUMAN (68-506): 7.25e-20: 96: 12.82
+	Ce
		136793 RAC1_CAEEL (1-192): 6e-83: 245: 79.69		UNC89_CAEEL (169-513): 1.01e-19: 95.6: 12.29
+	Hs
		564587 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		MICA3_HUMAN (68-506): 7.25e-20: 96: 12.82
+	Hs
		892677 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		ASAP1_HUMAN (95-423): 4.61e-23: 105: 13.43
+	Hs
		892450 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		MICA3_HUMAN (68-506): 7.25e-20: 96: 12.82
+	Ce
		104464 G5EBV3_CAEEL (2-192): 1.3e-77: 231: 62.30		UNC89_CAEEL (169-513): 1.01e-19: 95.6: 12.29
+	Hs
		867087 CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75		SC24C_HUMAN (116-429): 9.64e-11: 66.7: 15.43
+	Hs
		195972 RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26		PLXB1_HUMAN (78-332): 1.47e-10: 66.3: 19.62