HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: WASF1 (Q92558)
Actin-binding protein WASF1 (Protein WAVE-1) (Verprolin homology domain-containing protein 1) (Wiskott-Aldrich syndrome protein family member 1) (WASP family protein member 1)
Gene: WASF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005741 - mitochondrial outer membrane GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0005925 - focal adhesion GO:0030027 - lamellipodium
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 559
+	Hs
		925483 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		WASF1_HUMAN (1-559): 2.63e-73: 245: 100.00
+	Hs
		892517 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		WASF1_HUMAN (1-559): 2.63e-73: 245: 100.00
+	Hs
		925740 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		WASF3_HUMAN (1-557): 1.12e-43: 164: 45.73
+	Hs
		925779 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		WASF2_HUMAN (1-541): 2.37e-42: 160: 42.14
+	At
		1105109 RAC2_ARATH (4-177): 1.16e-80: 239: 64.94		SCAR2_ARATH (1-222): 8.84e-43: 166: 21.98
+	At
		1105135 RAC4_ARATH (4-177): 8.27e-80: 237: 64.94		SCAR2_ARATH (1-222): 8.84e-43: 166: 21.98
+	Hs
		545734 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		WASF2_HUMAN (1-541): 2.37e-42: 160: 42.14
+	Hs
		892710 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		WASF2_HUMAN (1-541): 2.37e-42: 160: 42.14
+	Hs
		166043 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		SYNJ2_HUMAN (46-507): 2.06e-31: 132: 13.92
+	Hs
		925219 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		NOTC2_HUMAN (67-436): 1.54e-28: 123: 14.68
+	Hs
		297823 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		K0754_HUMAN (76-470): 4.99e-27: 118: 14.46
+	Hs
		564491 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		NOTC2_HUMAN (67-436): 1.54e-28: 123: 14.68
+	Hs
		166039 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		SYNJ2_HUMAN (46-507): 2.06e-31: 132: 13.92
+	Hs
		545337 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		NOTC2_HUMAN (67-436): 1.54e-28: 123: 14.68
+	Hs
		297812 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		K0754_HUMAN (76-470): 4.99e-27: 118: 14.46
+	Hs
		892331 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		NOTC2_HUMAN (67-436): 1.54e-28: 123: 14.68
+	Hs
		950942 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		NOTC2_HUMAN (67-436): 1.54e-28: 123: 14.68
+	Hs
		297819 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		K0754_HUMAN (76-470): 4.99e-27: 118: 14.46
+	Hs
		297827 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		K0754_HUMAN (76-470): 4.99e-27: 118: 14.46
+	Hs
		867087 CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75		SC24C_HUMAN (164-476): 5.94e-10: 64.3: 12.65