HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: RFIP5 (Q9BXF6)
Rab11 family-interacting protein 5 (Rab11-FIP5) (Gamma-SNAP-associated factor 1) (Gaf-1) (Phosphoprotein pp75) (Rab11-interacting protein Rip11)
Gene: RAB11FIP5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RBD-FIP~Ras
Common GO terms	GO:0005741 - mitochondrial outer membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 653
+	Hs
		925583 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Hs
		564668 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Hs
		892570 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Hs
		951290 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Hs
		894384 CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Ce
		136793 RAC1_CAEEL (1-192): 6e-83: 245: 79.69		UNC89_CAEEL (164-653): 4.53e-35: 145: 9.40
+	Hs
		297823 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Hs
		297812 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Ce
		104464 G5EBV3_CAEEL (2-192): 1.3e-77: 231: 62.30		UNC89_CAEEL (164-653): 4.53e-35: 145: 9.40
+	Hs
		297819 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Ce
		136794 CDC42_CAEEL (1-192): 1.77e-75: 226: 67.71		UNC89_CAEEL (164-653): 4.53e-35: 145: 9.40
+	Hs
		297827 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Hs
		297820 RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Hs
		925372 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		564580 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		545456 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		892442 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		951094 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		894148 CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		900608 RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14