HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: NEB1 (Q9ULJ8)
Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A)
Gene: PPP1R9A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0007015 - actin filament organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 1098
+	Hs
		925725 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		NEB1_HUMAN (1-1098): 6.8e-118: 392: 100.00
+	Hs
		564735 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		NEB1_HUMAN (1-1098): 6.8e-118: 392: 100.00
+	Hs
		892678 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		NEB1_HUMAN (1-1098): 6.8e-118: 392: 100.00
+	Hs
		951455 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		NEB1_HUMAN (1-1098): 6.8e-118: 392: 100.00
+	Hs
		564636 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		DLG3_HUMAN (311-1098): 1.22e-71: 257: 13.03
+	Hs
		925239 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Hs
		892525 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		DLG3_HUMAN (311-1098): 1.22e-71: 257: 13.03
+	Hs
		564500 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Hs
		545346 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Hs
		951207 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		DLG3_HUMAN (311-1098): 1.22e-71: 257: 13.03
+	Hs
		892341 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Hs
		950954 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Mm
		925797 RAC1_MOUSE (1-192): 1.69e-84: 249: 92.19		DLG4_MOUSE (376-1098): 3.11e-50: 192: 13.00
+	Mm
		1111996 Q3TLP8_MOUSE (1-192): 5.9e-80: 238: 83.41		DLG4_MOUSE (376-1098): 3.11e-50: 192: 13.00
+	Mm
		925799 RAC1_MOUSE (1-192): 1.69e-84: 249: 92.19		NEB2_MOUSE (1-826): 5.97e-43: 171: 43.42
+	Mm
		892727 CDC42_MOUSE (1-192): 4.69e-77: 230: 68.75		NEB2_MOUSE (1-826): 5.97e-43: 171: 43.42
+	Hs
		925236 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		PTN13_HUMAN (2-937): 2.68e-18: 93.5: 11.65
+	Hs
		876341 CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75		AFAD_HUMAN (419-593): 1.96e-23: 110: 30.11
+	Hs
		564499 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		PTN13_HUMAN (2-937): 2.68e-18: 93.5: 11.65
+	Hs
		892339 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		PTN13_HUMAN (2-937): 2.68e-18: 93.5: 11.65