HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: FND3A (Q9Y2H6)
Fibronectin type-III domain-containing protein 3A (Human gene expressed in odontoblasts)
Gene: FNDC3A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~fn3
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 1198
+	Hs
		951469 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		FND3A_HUMAN (1-1198): 0: 783: 100.00
+	Hs
		894601 CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75		FND3A_HUMAN (1-1198): 0: 783: 100.00
+	Hs
		901062 RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26		FND3A_HUMAN (1-1198): 0: 783: 100.00
+	Hs
		489942 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		PTPRF_HUMAN (564-1183): 6.27e-77: 282: 14.69
+	Hs
		489899 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		PTPRF_HUMAN (564-1183): 6.27e-77: 282: 14.69
+	Hs
		489896 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		PTPRF_HUMAN (564-1183): 6.27e-77: 282: 14.69
+	Hs
		925247 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		PTPRS_HUMAN (559-1194): 2.52e-74: 274: 14.39
+	Hs
		564508 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		PTPRS_HUMAN (559-1194): 2.52e-74: 274: 14.39
+	Hs
		489932 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		PTPRF_HUMAN (564-1183): 6.27e-77: 282: 14.69
+	Hs
		489951 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		PTPRF_HUMAN (564-1183): 6.27e-77: 282: 14.69
+	Hs
		489933 CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75		PTPRF_HUMAN (564-1183): 6.27e-77: 282: 14.69
+	Hs
		489936 RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26		PTPRF_HUMAN (564-1183): 6.27e-77: 282: 14.69
+	Hs
		892348 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		PTPRS_HUMAN (559-1194): 2.52e-74: 274: 14.39
+	Hs
		893964 CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75		PTPRS_HUMAN (559-1194): 2.52e-74: 274: 14.39
+	Hs
		436131 RHOC_HUMAN (5-192): 1.83e-73: 221: 54.79		PTPRF_HUMAN (564-1183): 6.27e-77: 282: 14.69
+	Hs
		900436 RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26		PTPRS_HUMAN (559-1194): 2.52e-74: 274: 14.39
+	Hs
		436285 RHOC_HUMAN (5-192): 1.83e-73: 221: 54.79		PTPRS_HUMAN (559-1194): 2.52e-74: 274: 14.39
+	Hs
		564637 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		NEO1_HUMAN (7-773): 1.45e-64: 243: 14.86
+	Hs
		900635 RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26		SDK1_HUMAN (145-766): 1.67e-61: 233: 17.32
+	Hs
		363046 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		FINC_HUMAN (112-737): 5.66e-40: 164: 15.42