Interactor 1: ERF3A (P15170)
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Eukaryotic peptide chain release factor subunit 3a) (eRF3a) (EC 3.6.5.-) (G1 to S phase transition protein 1 homolog)
Gene: GSPT1

Interactor 2: IF2G (P41091)
Eukaryotic translation initiation factor 2 subunit 3 (EC 3.6.5.3) (Eukaryotic translation initiation factor 2 subunit gamma X) (eIF2-gamma X) (eIF2gX)
Gene: EIF2S3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains GTP_EFTU~eIF2_C, GTP_EFTU~GTP_EFTU, GTP_EFTU~GTP_EFTU_D2, GTP_EFTU_D2~eIF2_C, GTP_EFTU_D2~GTP_EFTU_D2, GTP_EFTU~GTP_EFTU_D3, GTP_EFTU_D2~GTP_EFTU_D3
Common GO terms GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 499
Hs

1 472
+ Hs
+ Sc
+ Hs
+ Sc
+ Hs
+ Sc
+ Hs
+ Sc

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Last updated: 15 Jul 2024