Interactor 1: ERF3A (P15170)
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Eukaryotic peptide chain release factor subunit 3a) (eRF3a) (EC 3.6.5.-) (G1 to S phase transition protein 1 homolog)
Gene: GSPT1
Interactor 2: ERF1 (P62495)
Eukaryotic peptide chain release factor subunit 1 (Eukaryotic release factor 1) (eRF1) (Protein Cl1) (TB3-1)
Gene: ETF1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.968 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 29395067, 9712840, 34349018, 18256688, 35271311, 35763353, 23091004, 24335085 |
| Identification Methods | proximity labelling technology, affinity chromatography technology, two hybrid, cross-linking study, 3D electron microscopy, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | GTP_EFTU~eRF1_1, GTP_EFTU~eRF1_2, GTP_EFTU_D2~eRF1_1, GTP_EFTU_D2~eRF1_2, GTP_EFTU_D3~eRF1_2, GTP_EFTU_D3~eRF1_3 |
| Common GO terms | GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0003723 - RNA binding GO:0003747 - translation release factor activity GO:0005737 - cytoplasm GO:0005829 - cytosol and 5 others more... |
| Homologous interactions | 8 |
Homologous interactions
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Last updated: 15 Jul 2024
