HitPredict

Interactor 1: A1Z9S6 (A1Z9S6)
Su(Var)2-HP2, isoform A
Gene: Su(var)2-HP2

Interactor 2: SGG (P18431)
Protein kinase shaggy (EC 2.7.11.1) (Protein zeste-white 3)
Gene: SGG

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.50	0.580

Property	Details
Experiments	21447707, 25294943
Identification Methods	affinity chromatography technology, interactome parallel affinity capture, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 3257 Dm			1 514
+	Dm
		576876 Q9W2Z3_DROME (191-3236): 1e-140: 499: 8.68		SGG_DROME (1-514): 6.06e-152: 445: 100.00
+	Hs
		164688 MAST4_HUMAN (51-1387): 6.1e-111: 400: 9.33		GSK3B_HUMAN (1-397): 1.68e-143: 420: 75.94
+	Hs
		164687 MAST4_HUMAN (51-1387): 6.1e-111: 400: 9.33		GSK3A_HUMAN (19-419): 1.05e-137: 408: 70.57
+	Dm
		576908 FUTSC_DROME (99-3178): 7.17e-68: 259: 11.42		SGG_DROME (1-514): 6.06e-152: 445: 100.00
+	Dm
		113978 M9PB30_DROME (2569-3255): 3.46e-40: 168: 9.24		SGG_DROME (1-514): 6.06e-152: 445: 100.00
+	Dm
		115292 M9PEP8_DROME (201-3225): 1.9e-24: 115: 10.09		SGG_DROME (1-514): 6.06e-152: 445: 100.00
+	Hs
		625511 KMT2E_HUMAN (1841-3245): 5.25e-24: 114: 7.24		CDK2_HUMAN (51-349): 1.48e-147: 426: 33.23
+	Dm
		112382 M9MSG3_DROME (566-3132): 1.15e-13: 80.2: 10.04		SGG_DROME (1-514): 6.06e-152: 445: 100.00
+	Dm
		576606 Q9VH10_DROME (767-2291): 3.05e-13: 78.9: 15.36		SGG_DROME (1-514): 6.06e-152: 445: 100.00
+	Dm
		576442 LUBEL_DROME (41-2376): 4.17e-13: 78.4: 8.62		SGG_DROME (1-514): 6.06e-152: 445: 100.00
+	Hs
		65021 A7Y9J9_HUMAN (1052-3252): 7.91e-20: 100: 10.01		GSK3B_HUMAN (1-397): 1.68e-143: 420: 75.94
+	Dm
		65548 A8JNM5_DROME (525-1905): 2.3e-11: 72.7: 15.14		SGG_DROME (1-514): 6.06e-152: 445: 100.00
+	Hs
		625528 TITIN_HUMAN (276-1837): 7.37e-17: 91: 10.46		CDK2_HUMAN (51-349): 1.48e-147: 426: 33.23
+	Dm
		54307 A1Z9J3_DROME (818-1507): 3.07e-10: 68.9: 14.19		SGG_DROME (1-514): 6.06e-152: 445: 100.00
+	Hs
		625642 SRRM2_HUMAN (2334-3255): 3.15e-12: 75.4: 7.95		CDK2_HUMAN (51-349): 1.48e-147: 426: 33.23
+	Hs
		554284 MUC1_HUMAN (2552-3245): 5.26e-11: 71.3: 12.52		GSK3B_HUMAN (1-397): 1.68e-143: 420: 75.94
+	Hs
		835988 TARA_HUMAN (1071-2018): 4.31e-09: 65: 12.47		GSK3B_HUMAN (1-397): 1.68e-143: 420: 75.94
+	Hs
		835573 SRRM2_HUMAN (2334-3255): 3.15e-12: 75.4: 7.95		GSK3A_HUMAN (19-419): 1.05e-137: 408: 70.57