Interactor 1: ERF3A (P15170)
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Eukaryotic peptide chain release factor subunit 3a) (eRF3a) (EC 3.6.5.-) (G1 to S phase transition protein 1 homolog)
Gene: GSPT1

Interactor 2: RENT1 (Q92900)
Regulator of nonsense transcripts 1 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (hUpf1)
Gene: UPF1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 0.60 0.716

The method score is based on:

Property Details
Experiments 35271311, 18256688, 19417104, 18423202, 16452507
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0003723 - RNA binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006449 - regulation of translational termination
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 499
Hs

1 1129
+ Hs
+ Sc
+ Sc
+ Hs
+ Sc
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024