HitPredict

Interactor 1: MYOG (P15173)
Myogenin (Class C basic helix-loop-helix protein 3) (bHLHc3) (Myogenic factor 4) (Myf-4)
Gene: MYOG

Interactor 2: ID1 (P41134)
DNA-binding protein inhibitor ID-1 (Class B basic helix-loop-helix protein 24) (bHLHb24) (Inhibitor of DNA binding 1) (Inhibitor of differentiation 1)
Gene: ID1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.794

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid, mammalian protein protein interaction trap
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0046983 - protein dimerization activity
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 224 Hs			1 155
+	Hs
		526742 MYF5_HUMAN (4-219): 7.48e-59: 187: 40.00		ID1_HUMAN (1-155): 1.17e-77: 229: 100.00
+	Hs
		545945 MYOD1_HUMAN (4-216): 3.41e-45: 154: 34.15		ID1_HUMAN (1-155): 1.17e-77: 229: 100.00
+	Mm
		485951 MYOD1_MOUSE (4-212): 6.95e-50: 166: 35.42		Q6GTZ3_MOUSE (15-155): 1.41e-70: 211: 90.78
+	Hs
		780971 ASCL4_HUMAN (47-164): 5.84e-32: 116: 30.23		ID1_HUMAN (1-155): 1.17e-77: 229: 100.00
+	Hs
		546072 MYOG_HUMAN (1-224): 7.77e-76: 230: 100.00		ID4_HUMAN (19-155): 1.46e-32: 114: 34.94
+	Hs
		524547 LYL1_HUMAN (48-195): 4.71e-27: 106: 21.48		ID1_HUMAN (1-155): 1.17e-77: 229: 100.00
+	Hs
		526743 MYF5_HUMAN (4-219): 7.48e-59: 187: 40.00		ID2_HUMAN (19-154): 3.39e-45: 146: 42.07
+	Hs
		526744 MYF5_HUMAN (4-219): 7.48e-59: 187: 40.00		ID3_HUMAN (19-128): 1.94e-45: 146: 47.27
+	Mm
		485939 MYOD1_MOUSE (4-212): 6.95e-50: 166: 35.42		ID2_MOUSE (19-154): 3.1e-46: 148: 41.38
+	Mm
		485938 MYOD1_MOUSE (4-212): 6.95e-50: 166: 35.42		ID3_MOUSE (19-128): 8.16e-46: 147: 46.36
+	Hs
		545958 MYOD1_HUMAN (4-216): 3.41e-45: 154: 34.15		ID2_HUMAN (19-154): 3.39e-45: 146: 42.07
+	Hs
		545959 MYOD1_HUMAN (4-216): 3.41e-45: 154: 34.15		ID3_HUMAN (19-128): 1.94e-45: 146: 47.27
+	Hs
		616610 MYF6_HUMAN (1-222): 5.25e-52: 170: 43.50		ID4_HUMAN (19-155): 1.46e-32: 114: 34.94
+	Hs
		970583 ASCL4_HUMAN (47-164): 5.84e-32: 116: 30.23		ID2_HUMAN (19-154): 3.39e-45: 146: 42.07
+	Hs
		524557 LYL1_HUMAN (48-195): 4.71e-27: 106: 21.48		ID3_HUMAN (19-128): 1.94e-45: 146: 47.27
+	Hs
		814916 NGN3_HUMAN (12-202): 5.77e-28: 107: 19.69		ID4_HUMAN (19-155): 1.46e-32: 114: 34.94
+	Hs
		524549 LYL1_HUMAN (48-195): 4.71e-27: 106: 21.48		ID4_HUMAN (19-155): 1.46e-32: 114: 34.94
+	Hs
		814909 FIGLA_HUMAN (78-176): 5.76e-22: 91.5: 31.00		ID4_HUMAN (19-155): 1.46e-32: 114: 34.94
+	Dm
		485922 AST4_DROME (76-144): 6.74e-19: 85.3: 33.33		EMC_DROME (68-134): 3.59e-23: 91.8: 47.76