HitPredict

Interactor 1: NTRK2 (P15209)
BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB/GP95-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase)
Gene: NTRK2

Interactor 2: AP2M1 (P84091)
AP-2 complex subunit mu (AP-2 mu chain) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (Mu2-adaptin) (Plasma membrane adaptor AP-2 50 kDa protein)
Gene: AP2M1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36417873
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0098794 - postsynapse GO:0098978 - glutamatergic synapse
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 821 Mm			1 435
+	Hs
		385470 NTRK1_HUMAN (5-821): 2.12e-174: 524: 47.09		AP1M1_HUMAN (2-434): 5.69e-170: 484: 38.85
+	Hs
		508141 FGFR1_HUMAN (183-820): 3.3e-165: 501: 23.95		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Hs
		508180 FGFR1_HUMAN (183-820): 3.3e-165: 501: 23.95		AP1M1_HUMAN (2-434): 5.69e-170: 484: 38.85
+	Hs
		385759 NTRK1_HUMAN (5-821): 2.12e-174: 524: 47.09		AP3M1_HUMAN (1-434): 1.4e-123: 366: 24.66
+	Hs
		609222 FGFR3_HUMAN (189-821): 1.75e-167: 506: 25.64		AP3M2_HUMAN (1-434): 2.92e-119: 355: 24.89
+	Hs
		1088134 DDR2_HUMAN (490-806): 1.82e-75: 264: 43.40		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Rn
		544815 INSR_RAT (512-808): 6.92e-67: 244: 42.38		AP2M1_RAT (1-435): 1.03e-178: 507: 100.00
+	Rn
		544829 INSR_RAT (512-808): 6.92e-67: 244: 42.38		AP1M1_RAT (2-434): 6.49e-170: 484: 38.85
+	Hs
		608213 FGFR4_HUMAN (157-819): 2.2e-154: 472: 25.90		STON1_HUMAN (149-408): 2.5e-58: 205: 21.75