Interactor 1: NTRK2 (P15209)
BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB/GP95-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase)
Gene: NTRK2

Interactor 2: TIAM1 (Q60610)
Rho guanine nucleotide exchange factor TIAM1 (T-lymphoma invasion and metastasis-inducing protein 1) (TIAM-1)
Gene: TIAM1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 16801538
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~PK_Tyr_Ser-Thr
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0010976 - positive regulation of neuron projection development
GO:0014069 - postsynaptic density
GO:0030971 - receptor tyrosine kinase binding
and 6 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 821
Mm

1 1591
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+ Ce
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024