Interactor 1: INGR1 (P15260)
Interferon gamma receptor 1 (IFN-gamma receptor 1) (IFN-gamma-R1) (CDw119) (Interferon gamma receptor alpha-chain) (IFN-gamma-R-alpha) (CD antigen CD119)
Gene: IFNGR1

Interactor 2: INGR2 (P38484)
Interferon gamma receptor 2 (IFN-gamma receptor 2) (IFN-gamma-R2) (Interferon gamma receptor accessory factor 1) (AF-1) (Interferon gamma receptor beta-chain) (IFN-gamma-R-beta) (Interferon gamma transducer 1)
Gene: IFNGR2

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 12438563, 16467876
Identification Methods fluorescent resonance energy transfer
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IFNGR1~Interfer-bind, IFNGR1~Tissue_fac, Interfer-bind~Tissue_fac, Tissue_fac~Tissue_fac
Common GO terms GO:0001774 - microglial cell activation
GO:0004896 - cytokine receptor activity
GO:0004906 - type II interferon receptor activity
GO:0005886 - plasma membrane
GO:0009615 - response to virus
and 4 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 489
Hs

1 337
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024