HitPredict

Interactor 1: APKC (A1Z9X0)
Atypical protein kinase C (EC 2.7.11.13)
Gene: APKC

Interactor 2: PP2A (P23696)
Serine/threonine-protein phosphatase PP2A (EC 3.1.3.16) (Protein microtubule star)
Gene: mts

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 19374896, 19690050
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0035331 - negative regulation of hippo signaling
GO:0045880 - positive regulation of smoothened signaling pathway
GO:0046872 - metal ion binding
GO:0055059 - asymmetric neuroblast division
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 606
Dm

1 309
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Dm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Sp
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024