HitPredict

Interactor 1: INGR1 (P15260)
Interferon gamma receptor 1 (IFN-gamma receptor 1) (IFN-gamma-R1) (CDw119) (Interferon gamma receptor alpha-chain) (IFN-gamma-R-alpha) (CD antigen CD119)
Gene: IFNGR1

Interactor 2: RHOU (Q7L0Q8)
Rho-related GTP-binding protein RhoU (CDC42-like GTPase 1) (GTP-binding protein-like 1) (Rho GTPase-like protein ARHU) (Ryu GTPase) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1)
Gene: RHOU

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 33961781, 31871319
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 489 Hs			1 258
+	Hs
		436142 INGR1_HUMAN (1-489): 1.69e-169: 488: 100.00		RHOC_HUMAN (51-231): 3.2e-89: 264: 46.96
+	Hs
		546445 INGR1_HUMAN (1-489): 1.69e-169: 488: 100.00		RAC3_HUMAN (48-223): 1.28e-83: 249: 57.96
+	Hs
		546452 INGR1_HUMAN (1-489): 1.69e-169: 488: 100.00		RHOG_HUMAN (48-233): 5.28e-83: 248: 48.93
+	Hs
		546450 INGR1_HUMAN (1-489): 1.69e-169: 488: 100.00		RAC1_HUMAN (50-234): 2.11e-79: 239: 56.76
+	Hs
		546448 INGR1_HUMAN (1-489): 1.69e-169: 488: 100.00		RB11A_HUMAN (39-256): 1.13e-77: 235: 26.87
+	Hs
		546447 INGR1_HUMAN (1-489): 1.69e-169: 488: 100.00		RHOA_HUMAN (51-232): 1.24e-77: 234: 46.15
+	Hs
		546446 INGR1_HUMAN (1-489): 1.69e-169: 488: 100.00		CDC42_HUMAN (50-236): 2.23e-74: 226: 58.82
+	Hs
		546429 INGR1_HUMAN (1-489): 1.69e-169: 488: 100.00		RHOQ_HUMAN (50-221): 2.69e-66: 206: 56.40
+	Hs
		546483 INGR1_HUMAN (1-489): 1.69e-169: 488: 100.00		RHOJ_HUMAN (40-238): 2.64e-63: 199: 51.26