HitPredict

Interactor 1: SEC23 (P15303)
Protein transport protein SEC23
Gene: SEC23

Interactor 2: SAR1 (P20606)
Small COPII coat GTPase SAR1 (EC 3.6.5.-) (GTP-binding protein SAR1) (Secretion-associated RAS-related protein 1)
Gene: SAR1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 21532587, 8004676, 12426382, 11907269, 9428766, 12408798, 12239560, 24947508
Identification Methods pull down, affinity chromatography technology, biochemical, enzymatic study, x-ray crystallography
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Arf~Gelsolin, Arf~Sec23_helical, Arf~Sec23_trunk, Arf~zf-Sec23_Sec24
Common GO terms GO:0000139 - Golgi membrane
GO:0003400 - regulation of COPII vesicle coating
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006886 - intracellular protein transport
and 4 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 768
Sc

1 190
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024