Interactor 1: SEC23 (P15303)
Protein transport protein SEC23
Gene: SEC23

Interactor 2: SFB3 (P38810)
SED5-binding protein 3 (Lethal with SEC13 protein 1) (SEC24-related protein 3)
Gene: SFB3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.973

The method score is based on:

Property Details
Experiments 10330397, 10753972, 11283351, 11086000, 37968396, 23904270, 18719252, 24947508, 16429126
Identification Methods two hybrid, coimmunoprecipitation, two hybrid pooling approach, affinity chromatography technology, pull down, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Gelsolin~Gelsolin, Gelsolin~Sec23_helical, Gelsolin~Sec23_trunk, Sec23_BS~Sec23_helical, Sec23_BS~Sec23_trunk, Sec23_BS~zf-Sec23_Sec24, Sec23_helical~Sec23_trunk, Sec23_trunk~Sec23_trunk, zf-Sec23_Sec24~zf-Sec23_Sec24
Common GO terms GO:0000139 - Golgi membrane
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006886 - intracellular protein transport
GO:0008270 - zinc ion binding
and 3 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 768
Sc

1 929
+ Hs
+ Hs
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+ Hs
+ Hs
+ Sc
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+ Sp
+ Sp
+ Sp
+ Ce
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024