HitPredict

Interactor 1: SEC23 (P15303)
Protein transport protein SEC23
Gene: SEC23

Interactor 2: SEC24 (P40482)
Protein transport protein SEC24 (Abnormal nuclear morphology 1)
Gene: SEC24

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.990

The method score is based on:

Property Details
Experiments 21532587, 8930902, 10097109, 11086000, 1498369, 10753972, 11283351, 10749860, 23904270, 27855785, 16429126, 18719252, 37968396, 20826334, 12778054, 12671686, 11535824, 12408798, 12239560, 10330397 and 1 others

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Identification Methods pull down, two hybrid, affinity chromatography technology, biochemical, coimmunoprecipitation, two hybrid pooling approach, tandem affinity purification, x-ray crystallography
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Gelsolin~Gelsolin, Gelsolin~Sec23_helical, Gelsolin~Sec23_trunk, Sec23_BS~Sec23_helical, Sec23_BS~Sec23_trunk, Sec23_BS~zf-Sec23_Sec24, Sec23_helical~Sec23_trunk, Sec23_trunk~Sec23_trunk, zf-Sec23_Sec24~zf-Sec23_Sec24
Common GO terms GO:0000139 - Golgi membrane
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006886 - intracellular protein transport
GO:0008270 - zinc ion binding
and 6 others

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Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 768
Sc

1 926
+ Hs
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+ Sc
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+ Sp
+ Sp
+ Sc
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+ Sp
+ Ce
+ Hs
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+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024