HitPredict

Interactor 1: SEC23 (P15303)
Protein transport protein SEC23
Gene: SEC23

Interactor 2: TMEDA (P54837)
Endoplasmic reticulum vesicle protein 25
Gene: ERV25

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	11560939, 23904270
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0006886 - intracellular protein transport
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 768 Sc			1 211
+	Hs
		1074075 SC23B_HUMAN (4-767): 0: 982: 49.81		TMED9_HUMAN (7-211): 3.62e-75: 227: 25.46
+	Hs
		1073994 SC23A_HUMAN (4-768): 0: 971: 49.22		TMED9_HUMAN (7-211): 3.62e-75: 227: 25.46
+	Hs
		1071768 SC23B_HUMAN (4-767): 0: 982: 49.81		TMED2_HUMAN (24-211): 8.42e-63: 195: 17.90
+	Hs
		833226 SC23B_HUMAN (4-767): 0: 982: 49.81		TMEDA_HUMAN (18-211): 3.7e-62: 194: 37.25
+	Hs
		1074029 SC23A_HUMAN (4-768): 0: 971: 49.22		TMED7_HUMAN (15-209): 3.98e-66: 204: 17.95
+	Hs
		1071767 SC23A_HUMAN (4-768): 0: 971: 49.22		TMED2_HUMAN (24-211): 8.42e-63: 195: 17.90
+	Hs
		833225 SC23A_HUMAN (4-768): 0: 971: 49.22		TMEDA_HUMAN (18-211): 3.7e-62: 194: 37.25
+	Hs
		1074030 SC23A_HUMAN (4-768): 0: 971: 49.22		TMED3_HUMAN (18-211): 5.18e-61: 191: 21.54
+	Sc
		546788 SEC23_YEAST (1-768): 0: 927: 100.00		ERP1_YEAST (4-211): 6.24e-52: 168: 15.91
+	Sc
		546705 SEC23_YEAST (1-768): 0: 927: 100.00		EMP24_YEAST (33-211): 6.48e-24: 95.9: 19.23
+	Hs
		315702 SC24B_HUMAN (6-761): 0: 587: 17.58		TMED2_HUMAN (24-211): 8.42e-63: 195: 17.90
+	Hs
		867099 SC24C_HUMAN (4-761): 0: 562: 14.94		TMED2_HUMAN (24-211): 8.42e-63: 195: 17.90
+	Hs
		315559 SC24A_HUMAN (6-761): 0: 554: 18.20		TMED2_HUMAN (24-211): 8.42e-63: 195: 17.90
+	Hs
		297861 SC24D_HUMAN (4-724): 1.31e-180: 546: 16.30		TMED2_HUMAN (24-211): 8.42e-63: 195: 17.90
+	Sc
		774432 SEC24_YEAST (4-669): 5.47e-165: 502: 16.06		TMEDA_YEAST (1-211): 1.73e-63: 197: 100.00
+	Sc
		774447 SEC24_YEAST (4-669): 5.47e-165: 502: 16.06		ERP1_YEAST (4-211): 6.24e-52: 168: 15.91
+	Sc
		698422 SEC24_YEAST (4-669): 5.47e-165: 502: 16.06		EMP24_YEAST (33-211): 6.48e-24: 95.9: 19.23