HitPredict

Interactor 1: PPAP (P15309)
Prostatic acid phosphatase (PAP) (EC 3.1.3.2) (5'-nucleotidase) (5'-NT) (EC 3.1.3.5) (Acid phosphatase 3) (Ecto-5'-nucleotidase) (Protein tyrosine phosphatase ACP3) (EC 3.1.3.48) (Thiamine monophosphatase) (TMPase) [Cleaved into: PAPf39]
Gene: ACP3

Interactor 2: PPAP (P15309)
Prostatic acid phosphatase (PAP) (EC 3.1.3.2) (5'-nucleotidase) (5'-NT) (EC 3.1.3.5) (Acid phosphatase 3) (Ecto-5'-nucleotidase) (Protein tyrosine phosphatase ACP3) (EC 3.1.3.48) (Thiamine monophosphatase) (TMPase) [Cleaved into: PAPf39]
Gene: ACP3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.843

The method score is based on:

Property Details
Experiments 9804805, 18083097, 24657436
Identification Methods x-ray crystallography, cosedimentation, circular dichroism, fluorescence technology, transmission electron microscopy
Interaction Type association, physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains His_Phos_2~His_Phos_2
Common GO terms GO:0003993 - acid phosphatase activity
GO:0004725 - protein tyrosine phosphatase activity
GO:0005615 - extracellular space
GO:0005634 - nucleus
GO:0005764 - lysosome
and 27 others

more...
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 386
Hs

1 386
+ Dm
+ Sc
+ Sc
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024