HitPredict

Interactor 1: EZRI (P15311)
Ezrin (Cytovillin) (Villin-2) (p81)
Gene: EZR

Interactor 2: ICAM3 (P32942)
Intercellular adhesion molecule 3 (ICAM-3) (CDw50) (ICAM-R) (CD antigen CD50)
Gene: ICAM3

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

Property	Details
Experiments	9705328, 11784723
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 586 Hs			1 547
+	Hs
		399964 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		ICAM1_HUMAN (22-530): 2.97e-116: 356: 46.89
+	Hs
		399982 MOES_HUMAN (1-586): 4.45e-161: 474: 72.70		ICAM1_HUMAN (22-530): 2.97e-116: 356: 46.89
+	Hs
		640050 MOES_HUMAN (1-586): 4.45e-161: 474: 72.70		ICAM3_HUMAN (1-547): 7.47e-108: 334: 100.00
+	Mm
		530229 RADI_MOUSE (1-586): 1.52e-164: 483: 76.28		ICAM1_MOUSE (1-526): 6.98e-84: 272: 40.94
+	Hs
		530232 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		ICAM2_HUMAN (18-226): 7.33e-71: 230: 34.11
+	Hs
		530235 RADI_HUMAN (1-586): 7.83e-165: 484: 76.28		ICAM2_HUMAN (18-226): 7.33e-71: 230: 34.11
+	Mm
		640204 RADI_MOUSE (1-586): 1.52e-164: 483: 76.28		ICAM2_MOUSE (13-225): 2.75e-71: 231: 31.82
+	Hs
		530234 MOES_HUMAN (1-586): 4.45e-161: 474: 72.70		ICAM2_HUMAN (18-226): 7.33e-71: 230: 34.11
+	Hs
		547134 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		KIRR3_HUMAN (27-509): 4.79e-37: 148: 13.81
+	Hs
		547278 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		ICAM5_HUMAN (38-527): 7.28e-37: 148: 14.14
+	Hs
		719746 RADI_HUMAN (1-586): 7.83e-165: 484: 76.28		KIRR3_HUMAN (27-509): 4.79e-37: 148: 13.81
+	Mm
		640203 RADI_MOUSE (1-586): 1.52e-164: 483: 76.28		VCAM1_MOUSE (16-485): 4.96e-36: 145: 17.11
+	Hs
		546923 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		VCAM1_HUMAN (232-483): 5.01e-21: 99.3: 18.86
+	Hs
		581442 MOES_HUMAN (1-586): 4.45e-161: 474: 72.70		VCAM1_HUMAN (232-483): 5.01e-21: 99.3: 18.86
+	Hs
		719447 MERL_HUMAN (2-586): 3.18e-146: 436: 44.37		PGBM_HUMAN (27-479): 4.29e-31: 131: 15.23
+	Hs
		81626 B7Z5V2_HUMAN (1-586): 4.12e-153: 452: 94.37		VCAM1_HUMAN (232-483): 5.01e-21: 99.3: 18.86
+	Dm
		802983 MOEH_DROME (2-586): 8.49e-145: 432: 56.01		Q9BN17_DROME (36-483): 1.33e-26: 116: 12.98
+	Hs
		640132 MOES_HUMAN (1-586): 4.45e-161: 474: 72.70		TITIN_HUMAN (102-498): 5.77e-10: 64.5: 11.51
+	Dm
		1098337 MERH_DROME (3-586): 1.08e-131: 400: 40.58		Q9VQW7_DROME (36-483): 1.33e-26: 116: 12.98
+	Hs
		581462 PTN4_HUMAN (4-480): 1.13e-123: 388: 22.20		VCAM1_HUMAN (232-483): 5.01e-21: 99.3: 18.86