HitPredict

Interactor 1: EZRI (P15311)
Ezrin (Cytovillin) (Villin-2) (p81)
Gene: EZR

Interactor 2: RADI (P35241)
Radixin
Gene: RDX

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.975

The method score is based on:

Property Details
Experiments 34079125, 26496610, 29568061, 23414517, 33961781, 35271311, 35235311, 34349018, 37071682, unassigned1655
Identification Methods proximity labelling technology, affinity chromatography technology, two hybrid, cross-linking study, anti tag coimmunoprecipitation, pull down, two hybrid fragment pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ERM_C~ERM_C, ERM_C~FERM_C, ERM_C~FERM_M, ERM_helical~FERM_N, FERM_C~FERM_C, FERM_C~FERM_M, FERM_C~FERM_N, FERM_M~FERM_M, FERM_M~FERM_N, FERM_N~FERM_N
Common GO terms GO:0003723 - RNA binding
GO:0003779 - actin binding
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0005902 - microvillus
and 20 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 586
Hs

1 583
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+ Ce
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+ Dm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024