Interactor 1: EZRI (P15311)
Ezrin (Cytovillin) (Villin-2) (p81)
Gene: EZR

Interactor 2: NEDD4 (P46934)
E3 ubiquitin-protein ligase NEDD4 (EC 2.3.2.26) (Cell proliferation-inducing gene 53 protein) (HECT-type E3 ubiquitin transferase NEDD4) (Neural precursor cell expressed developmentally down-regulated protein 4) (NEDD-4)
Gene: NEDD4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 0.60 0.611

The method score is based on:

Property Details
Experiments 30385740, 24981860
Identification Methods affinity chromatography technology, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0019904 - protein domain specific binding
and 5 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 586
Hs

1 1319
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024