Interactor 1: EZRI (P15311)
Ezrin (Cytovillin) (Villin-2) (p81)
Gene: EZR

Interactor 2: TNFL6 (P48023)
Tumor necrosis factor ligand superfamily member 6 (Apoptosis antigen ligand) (APTL) (CD95 ligand) (CD95-L) (Fas antigen ligand) (Fas ligand) (FasL) (CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form (Receptor-binding FasL ectodomain) (Soluble Fas ligand) (sFasL); ADAM10-processed FasL form (APL); FasL intracellular domain (FasL ICD) (SPPL2A-processed FasL form) (SPA)]
Gene: FASLG

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 0.60 0.571

The method score is based on:

Property Details
Experiments 15659383, 11013215
Identification Methods biochemical, affinity chromatography technology
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0048471 - perinuclear region of cytoplasm
GO:0070062 - extracellular exosome
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 586
Hs

1 281
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024