HitPredict

Interactor 1: EZRI (P15311)
Ezrin (Cytovillin) (Villin-2) (p81)
Gene: EZR

Interactor 2: MPP3 (Q13368)
MAGUK p55 subfamily member 3 (Discs large homolog 3) (Protein MPP3)
Gene: MPP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	21988832
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005912 - adherens junction GO:0016324 - apical plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 586 Hs			1 585
+	Hs
		159150 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		CSKP_HUMAN (1-584): 7.57e-130: 404: 27.17
+	Hs
		719486 MERL_HUMAN (2-586): 3.18e-146: 436: 44.37		MPP2_HUMAN (1-584): 1.51e-141: 424: 30.05
+	Hs
		719641 MERL_HUMAN (2-586): 3.18e-146: 436: 44.37		PALS2_HUMAN (10-584): 8.44e-142: 423: 31.22
+	Hs
		159272 E41L5_HUMAN (5-586): 7.7e-142: 430: 21.28		CSKP_HUMAN (1-584): 7.57e-130: 404: 27.17
+	Hs
		663981 PTN4_HUMAN (4-480): 1.13e-123: 388: 22.20		MPP7_HUMAN (1-584): 1.05e-148: 442: 52.27
+	Hs
		719540 MERL_HUMAN (2-586): 3.18e-146: 436: 44.37		PALS1_HUMAN (24-585): 9.47e-129: 394: 34.21
+	Hs
		1232502 E41L5_HUMAN (5-586): 7.7e-142: 430: 21.28		PALS1_HUMAN (24-585): 9.47e-129: 394: 34.21
+	Mm
		250719 E41L2_MOUSE (2-577): 3.85e-120: 380: 19.56		PALS2_MOUSE (10-584): 9.81e-143: 426: 31.48
+	Hs
		159142 EPB41_HUMAN (3-553): 9.55e-129: 400: 22.99		CSKP_HUMAN (1-584): 7.57e-130: 404: 27.17
+	Hs
		1132894 E41LA_HUMAN (1-576): 5.03e-116: 361: 16.47		MPP7_HUMAN (1-584): 1.05e-148: 442: 52.27
+	Hs
		159273 E41LA_HUMAN (1-576): 5.03e-116: 361: 16.47		CSKP_HUMAN (1-584): 7.57e-130: 404: 27.17
+	Hs
		1232517 E41L3_HUMAN (2-466): 2.17e-114: 367: 22.83		PALS1_HUMAN (24-585): 9.47e-129: 394: 34.21
+	Hs
		1232503 E41LA_HUMAN (1-576): 5.03e-116: 361: 16.47		PALS1_HUMAN (24-585): 9.47e-129: 394: 34.21
+	Hs
		547030 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		DLG1_HUMAN (59-288): 7.66e-23: 105: 15.06
+	Hs
		505627 EPB41_HUMAN (3-553): 9.55e-129: 400: 22.99		DLG1_HUMAN (59-288): 7.66e-23: 105: 15.06
+	Dm
		677683 MOEH_DROME (2-586): 8.49e-145: 432: 56.01		DLG1_DROME (85-218): 3.13e-12: 71.6: 14.29
+	Mm
		1143533 E41LB_MOUSE (4-412): 4.85e-121: 369: 22.01		DLG4_MOUSE (94-224): 4.36e-22: 102: 14.38
+	Mm
		1143556 E41L3_MOUSE (2-522): 3.29e-115: 366: 21.48		DLG4_MOUSE (94-224): 4.36e-22: 102: 14.38
+	Hs
		1021565 E41LA_HUMAN (1-576): 5.03e-116: 361: 16.47		DLG1_HUMAN (59-288): 7.66e-23: 105: 15.06