HitPredict

Interactor 1: EZRI (P15311)
Ezrin (Cytovillin) (Villin-2) (p81)
Gene: EZR

Interactor 2: ABI1 (Q8IZP0)
Abl interactor 1 (Abelson interactor 1) (Abi-1) (Abl-binding protein 4) (AblBP4) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (Nap1-binding protein) (Nap1BP) (Spectrin SH3 domain-binding protein 1) (e3B1)
Gene: ABI1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29568061, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0045296 - cadherin binding GO:0070062 - extracellular exosome
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 586 Hs			1 508
+	Hs
		547247 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		ABI2_HUMAN (1-508): 1.41e-81: 264: 59.84
+	Hs
		203207 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		SYNJ1_HUMAN (38-463): 1.36e-41: 161: 11.55
+	Hs
		547273 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		ASAP1_HUMAN (107-505): 8.23e-33: 135: 16.83
+	Hs
		547059 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		LASP1_HUMAN (285-503): 9.91e-33: 127: 19.28
+	Hs
		719713 RADI_HUMAN (1-586): 7.83e-165: 484: 76.28		LASP1_HUMAN (285-503): 9.91e-33: 127: 19.28
+	Hs
		547250 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		ITSN2_HUMAN (44-508): 6.18e-18: 89.8: 11.98
+	Hs
		547088 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		SH319_HUMAN (446-503): 2.42e-10: 65.1: 36.21
+	Hs
		547074 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		ITSN1_HUMAN (399-504): 1.82e-09: 62.5: 20.35
+	Hs
		297816 RADI_HUMAN (1-586): 7.83e-165: 484: 76.28		K0754_HUMAN (80-400): 5.9e-17: 86.7: 7.60
+	Hs
		719728 RADI_HUMAN (1-586): 7.83e-165: 484: 76.28		SH319_HUMAN (446-503): 2.42e-10: 65.1: 36.21
+	Dm
		1363698 Q9W0R3_DROME (3-516): 4.6e-124: 390: 21.76		Q9VDF4_DROME (250-503): 5.78e-30: 125: 21.30
+	Hs
		719668 MERL_HUMAN (2-586): 3.18e-146: 436: 44.37		CD2AP_HUMAN (451-508): 2.26e-14: 77.9: 40.68
+	Hs
		204664 E41L2_HUMAN (2-577): 1.05e-117: 374: 19.70		SRC8_HUMAN (291-502): 1.23e-34: 138: 20.72
+	Hs
		297842 E41LA_HUMAN (1-576): 5.03e-116: 361: 16.47		K0754_HUMAN (80-400): 5.9e-17: 86.7: 7.60