HitPredict

Interactor 1: VATB1 (P15313)
V-type proton ATPase subunit B, kidney isoform (V-ATPase subunit B 1) (Endomembrane proton pump 58 kDa subunit) (Vacuolar proton pump subunit B 1)
Gene: ATP6V1B1

Interactor 2: VATA (P38606)
V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 7.1.2.2) (V-ATPase 69 kDa subunit) (Vacuolar ATPase isoform VA68) (Vacuolar proton pump subunit alpha)
Gene: ATP6V1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.886

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 21674799
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ATP-synt_ab~ATP-synt_ab, ATP-synt_ab~ATP-synt_ab_N, ATP-synt_ab~ATP-synt_ab_Xtn, ATP-synt_ab_N~ATP-synt_ab_N, ATP-synt_ab_N~ATP-synt_ab_Xtn
Common GO terms GO:0000221 - vacuolar proton-transporting V-type ATPase, V1 domain
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0005902 - microvillus
GO:0007035 - vacuolar acidification
and 7 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 513
Hs

1 617
+ Mm
+ Hs
+ Mm
+ Dm
+ Tt
+ Sc
+ Ce
+ Hs
+ Hs
+ Nv
+ Dm
+ Ec
+ Hp
+ Ec
+ So
+ At
+ Se
+ Cp

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Last updated: 15 Jul 2024