Interactor 1: IRF1 (P15314)
Interferon regulatory factor 1 (IRF-1)
Gene: IRF1

Interactor 2: TBK1 (Q9WUN2)
Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (T2K) (TANK-binding kinase 1)
Gene: TBK1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.501

The method score is based on:

Property Details
Experiments 17468758
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0010468 - regulation of gene expression
GO:0032728 - positive regulation of interferon-beta production
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 329
Mm

1 729
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024