Interactor 1: KCNE1 (P15382)
Potassium voltage-gated channel subfamily E member 1 (Delayed rectifier potassium channel subunit IsK) (IKs producing slow voltage-gated potassium channel subunit beta Mink) (Minimal potassium channel)
Gene: KCNE1

Interactor 2: KCNH2 (Q12809)
Potassium voltage-gated channel subfamily H member 2 (Eag homolog) (Ether-a-go-go-related gene potassium channel 1) (ERG-1) (Eag-related protein 1) (Ether-a-go-go-related protein 1) (H-ERG) (hERG-1) (hERG1) (Voltage-gated potassium channel subunit Kv11.1)
Gene: KCNH2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 9230439
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ISK_Channel~Ion_trans
Common GO terms GO:0005251 - delayed rectifier potassium channel activity
GO:0005886 - plasma membrane
GO:0008076 - voltage-gated potassium channel complex
GO:0009986 - cell surface
GO:0060307 - regulation of ventricular cardiac muscle cell membrane repolarization
and 11 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 129
Hs

1 1159
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024