Interactor 1: FOSL1 (P15407)
Fos-related antigen 1 (FRA-1)
Gene: FOSL1

Interactor 2: USF1 (P22415)
Upstream stimulatory factor 1 (Class B basic helix-loop-helix protein 11) (bHLHb11) (Major late transcription factor 1)
Gene: USF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 0.60 0.729

The method score is based on:

Property Details
Experiments 25416956, 32296183, 9160889, 33961781, unassigned1304
Identification Methods two hybrid, pull down, affinity chromatography technology, coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 271
Hs

1 310
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024