HitPredict

Interactor 1: FOSL2 (P15408)
Fos-related antigen 2 (FRA-2)
Gene: FOSL2

Interactor 2: STK40 (Q8N2I9)
Serine/threonine-protein kinase 40 (EC 2.7.11.1) (SINK-homologous serine/threonine-protein kinase) (Sugen kinase 495) (SgK495)
Gene: STK40

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	28089446, 26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0035264 - multicellular organism growth
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 326 Hs			1 435
+	Hs
		345337 FOS_HUMAN (1-326): 3.85e-40: 146: 37.21		MARK3_HUMAN (3-433): 6.07e-121: 370: 19.55
+	Hs
		345487 FOS_HUMAN (1-326): 3.85e-40: 146: 37.21		STK40_HUMAN (1-435): 7.15e-121: 360: 100.00
+	Hs
		579357 ATF6A_HUMAN (10-275): 1.3e-24: 106: 13.12		STK40_HUMAN (1-435): 7.15e-121: 360: 100.00
+	At
		1105396 ABI5_ARATH (18-199): 1.43e-22: 99.4: 18.56		KIN10_ARATH (21-427): 8.81e-122: 365: 20.63
+	Hs
		548254 FOSL1_HUMAN (47-326): 6.16e-25: 103: 40.21		STK40_HUMAN (1-435): 7.15e-121: 360: 100.00
+	Hs
		862625 FOSB_HUMAN (1-326): 3.81e-24: 102: 31.69		STK40_HUMAN (1-435): 7.15e-121: 360: 100.00
+	Hs
		566775 JUNB_HUMAN (71-193): 6.45e-23: 99: 24.00		STK40_HUMAN (1-435): 7.15e-121: 360: 100.00
+	At
		1105922 ABI5_ARATH (18-199): 1.43e-22: 99.4: 18.56		CDPKB_ARATH (10-426): 1.24e-119: 359: 18.29
+	At
		955252 ABI5_ARATH (18-199): 1.43e-22: 99.4: 18.56		KIN11_ARATH (34-430): 1.98e-119: 359: 21.59
+	At
		187524 ABI5_ARATH (18-199): 1.43e-22: 99.4: 18.56		CIPKB_ARATH (16-397): 3.6e-120: 358: 19.27
+	Hs
		548326 FOSL2_HUMAN (1-326): 1.44e-51: 174: 100.00		TRIB1_HUMAN (155-325): 4.48e-30: 121: 39.31
+	Hs
		345527 FOS_HUMAN (1-326): 3.85e-40: 146: 37.21		TRIB1_HUMAN (155-325): 4.48e-30: 121: 39.31
+	Hs
		345378 FOS_HUMAN (1-326): 3.85e-40: 146: 37.21		AAPK2_HUMAN (162-379): 1.47e-24: 107: 31.36
+	Hs
		871409 Q6FG41_HUMAN (1-326): 3.85e-40: 146: 37.21		AAPK2_HUMAN (162-379): 1.47e-24: 107: 31.36
+	Hs
		579370 ATF6A_HUMAN (10-275): 1.3e-24: 106: 13.12		TRIB1_HUMAN (155-325): 4.48e-30: 121: 39.31
+	Hs
		548261 FOSL1_HUMAN (47-326): 6.16e-25: 103: 40.21		TRIB1_HUMAN (155-325): 4.48e-30: 121: 39.31
+	Hs
		862631 FOSB_HUMAN (1-326): 3.81e-24: 102: 31.69		TRIB1_HUMAN (155-325): 4.48e-30: 121: 39.31
+	Hs
		566786 JUNB_HUMAN (71-193): 6.45e-23: 99: 24.00		TRIB1_HUMAN (155-325): 4.48e-30: 121: 39.31
+	Mm
		987634 ATF4_MOUSE (2-189): 2.08e-25: 105: 19.58		TRIB3_MOUSE (161-325): 4.57e-26: 110: 38.10
+	Hs
		579283 ATF4_HUMAN (5-189): 1.34e-23: 101: 17.30		TRIB3_HUMAN (161-325): 4.49e-25: 107: 38.10