HitPredict

Interactor 1: FOSL2 (P15408)
Fos-related antigen 2 (FRA-2)
Gene: FOSL2

Interactor 2: TRIB1 (Q96RU8)
Tribbles homolog 1 (TRB-1) (G-protein-coupled receptor-induced gene 2 protein) (GIG-2) (SKIP1)
Gene: TRIB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0032496 - response to lipopolysaccharide
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 372
+	Hs
		345527 FOS_HUMAN (1-326): 3.85e-40: 146: 37.21		TRIB1_HUMAN (1-372): 7.49e-123: 360: 100.00
+	Hs
		547787 ATF2_HUMAN (4-268): 1.88e-24: 105: 18.11		KPCE_HUMAN (11-371): 2.39e-128: 387: 17.32
+	At
		1105396 ABI5_ARATH (18-199): 1.43e-22: 99.4: 18.56		KIN10_ARATH (76-364): 5.74e-128: 378: 29.87
+	At
		187524 ABI5_ARATH (18-199): 1.43e-22: 99.4: 18.56		CIPKB_ARATH (72-371): 8.51e-129: 378: 25.24
+	At
		955252 ABI5_ARATH (18-199): 1.43e-22: 99.4: 18.56		KIN11_ARATH (90-364): 1.62e-124: 369: 29.58
+	Hs
		579370 ATF6A_HUMAN (10-275): 1.3e-24: 106: 13.12		TRIB1_HUMAN (1-372): 7.49e-123: 360: 100.00
+	Hs
		548261 FOSL1_HUMAN (47-326): 6.16e-25: 103: 40.21		TRIB1_HUMAN (1-372): 7.49e-123: 360: 100.00
+	Hs
		862631 FOSB_HUMAN (1-326): 3.81e-24: 102: 31.69		TRIB1_HUMAN (1-372): 7.49e-123: 360: 100.00
+	Hs
		566786 JUNB_HUMAN (71-193): 6.45e-23: 99: 24.00		TRIB1_HUMAN (1-372): 7.49e-123: 360: 100.00
+	Mm
		987634 ATF4_MOUSE (2-189): 2.08e-25: 105: 19.58		TRIB3_MOUSE (89-360): 9.59e-93: 283: 54.91
+	Hs
		579283 ATF4_HUMAN (5-189): 1.34e-23: 101: 17.30		TRIB3_HUMAN (89-360): 1.98e-86: 267: 51.65
+	Hs
		548318 FOSL2_HUMAN (1-326): 1.44e-51: 174: 100.00		STK40_HUMAN (163-333): 2.9e-30: 122: 39.31
+	Hs
		345487 FOS_HUMAN (1-326): 3.85e-40: 146: 37.21		STK40_HUMAN (163-333): 2.9e-30: 122: 39.31
+	Hs
		579357 ATF6A_HUMAN (10-275): 1.3e-24: 106: 13.12		STK40_HUMAN (163-333): 2.9e-30: 122: 39.31
+	Hs
		548254 FOSL1_HUMAN (47-326): 6.16e-25: 103: 40.21		STK40_HUMAN (163-333): 2.9e-30: 122: 39.31
+	Hs
		862625 FOSB_HUMAN (1-326): 3.81e-24: 102: 31.69		STK40_HUMAN (163-333): 2.9e-30: 122: 39.31
+	Hs
		566775 JUNB_HUMAN (71-193): 6.45e-23: 99: 24.00		STK40_HUMAN (163-333): 2.9e-30: 122: 39.31