HitPredict

Interactor 1: GCN2 (P15442)
eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (General control non-derepressible protein 2) (Serine/threonine-protein kinase GCN2)
Gene: GCN2

Interactor 2: HSP7F (P32589)
Heat shock protein homolog SSE1 (Chaperone protein MSI3)
Gene: SSE1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19536198
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1659 Sc			1 693
+	Sc
		548521 GCN2_YEAST (1-1659): 0: 1202: 99.22		HSP79_YEAST (1-677): 0: 992: 77.11
+	Hs
		1120592 E2AK4_HUMAN (7-1607): 0: 788: 20.55		Q53FC7_HUMAN (4-643): 0: 838: 26.12
+	Sc
		449888 GCN2_YEAST (1-1659): 0: 1202: 99.22		HSP73_YEAST (1-642): 5.45e-72: 247: 28.33
+	Sc
		493105 GCN2_YEAST (1-1659): 0: 1202: 99.22		HSP72_YEAST (1-382): 1.15e-71: 246: 36.82
+	Sc
		490220 GCN2_YEAST (1-1659): 0: 1202: 99.22		HSP71_YEAST (1-382): 7.01e-71: 244: 36.55
+	Hs
		503334 HARS1_HUMAN (981-1493): 2.26e-133: 426: 20.61		HSP7C_HUMAN (2-645): 0: 851: 27.04
+	Hs
		503719 KS6A3_HUMAN (204-675): 9.63e-90: 311: 9.66		HSP7C_HUMAN (2-645): 0: 851: 27.04
+	Hs
		564041 KS6A3_HUMAN (204-675): 9.63e-90: 311: 9.66		HSP76_HUMAN (4-643): 0: 842: 26.28
+	Hs
		504119 KS6A1_HUMAN (259-574): 3.22e-85: 298: 13.20		HSP7C_HUMAN (2-645): 0: 851: 27.04
+	Hs
		564080 KS6A1_HUMAN (259-574): 3.22e-85: 298: 13.20		HSP76_HUMAN (4-643): 0: 842: 26.28
+	Sc
		419840 SNF1_YEAST (250-682): 7.43e-79: 276: 12.31		HSP7F_YEAST (1-693): 0: 829: 100.00
+	Hs
		229919 NUAK1_HUMAN (779-1000): 9.82e-19: 94.4: 27.88		HSP7C_HUMAN (2-645): 0: 851: 27.04
+	Hs
		504660 E2AK1_HUMAN (248-543): 6.72e-11: 69: 17.74		HSP7C_HUMAN (2-645): 0: 851: 27.04
+	Hs
		850687 KS6A3_HUMAN (204-675): 9.63e-90: 311: 9.66		HS105_HUMAN (6-687): 1.23e-133: 416: 36.05
+	Sc
		425058 SYH_YEAST (1035-1462): 1.41e-107: 356: 21.34		HSP72_YEAST (1-382): 1.15e-71: 246: 36.82
+	Sc
		425057 SYH_YEAST (1035-1462): 1.41e-107: 356: 21.34		HSP71_YEAST (1-382): 7.01e-71: 244: 36.55
+	Sc
		419765 SNF1_YEAST (250-682): 7.43e-79: 276: 12.31		HSP73_YEAST (1-642): 5.45e-72: 247: 28.33
+	Sc
		419775 SNF1_YEAST (250-682): 7.43e-79: 276: 12.31		HSP72_YEAST (1-382): 1.15e-71: 246: 36.82
+	Sc
		419774 SNF1_YEAST (250-682): 7.43e-79: 276: 12.31		HSP71_YEAST (1-382): 7.01e-71: 244: 36.55