Interactor 1: VAV (P15498)
Proto-oncogene vav
Gene: VAV1
Interactor 2: PLCG1 (P19174)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (PLC-148) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-II) (PLC-II) (Phospholipase C-gamma-1) (PLC-gamma-1)
Gene: PLCG1
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.64 | 1.00 | 0.806 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | C1_1~C2, C1_1~PH, C1_1~SH2, CAMSAP_CH~PH, PH~PH, PH~SH3_1, PH~RhoGEF, RhoGEF~SH3_1, C2~SH2, SH2~SH2, SH2~SH3_1, SH3_1~SH3_1 |
| Common GO terms | GO:0005085 - guanyl-nucleotide exchange factor activity GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005911 - cell-cell junction and 2 others more... |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
