Interactor 1: VAV (P15498)
Proto-oncogene vav
Gene: VAV1
Interactor 2: CBL (P22681)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING finger protein 55) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)
Gene: CBL
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 0.60 | 0.747 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9200440, 12881521, 16356860, 19635790, 16289966, 11331248, 18835194 |
| Identification Methods | affinity chromatography technology, pull down, far western blotting, genetic interference, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0001784 - phosphotyrosine residue binding GO:0005829 - cytosol GO:0005886 - plasma membrane |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
