HitPredict

Interactor 1: VAV (P15498)
Proto-oncogene vav
Gene: VAV1

Interactor 2: TYK2 (P29597)
Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)
Gene: TYK2

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 10673353, 9038355
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~PK_Tyr_Ser-Thr, PH~PK_Tyr_Ser-Thr, FERM_F1~SH2, PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006955 - immune response
GO:0035556 - intracellular signal transduction
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 845
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024